The following paragraphs are
from the reviewer's reports on our paper:

Title: An Integrative Computational Model of Multiciliary Beating
Authors: X. Yang, R. H. Dillon and L. Fauci


           This interesting and well written report makes
        significant progress in achieving a practical model of multiple
        cilia interacting in a viscous fluid field. It has the distinct
        advantage over alternate published models of cilia in that the
        cilia itself is constructed of mechanical elements that can be
        easily adapted to test mechanisms of internal functioning of the
        cilium as well as evaluating the viscous interactions with the
        external environment. The authors make a strong case that the
        model can simulate several observable behaviors of real cilia,
        such as synchronization and development of metachrony. A
        definite strength of the current report is that it very
        conscientiously reviews the relevant literature and places the
        current work accurately in the development of the field. Very
        few of the papers on this subject take such a global view of the
        current state of knowledge in the field.

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        I like the new synchronization function they devised to
        compare the degree of synchrony between two flagella,
        I think that adds to the paper and will be a useful tool in the future.

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   a mpeg movie link about this synchrony function:

   http://www.ccs.tulane.edu/~xyang4/movies/syn-metachrony/
   
   the synchronization function was inspired by a discussion
   with Lisa Fauci and Ricardo Cortez on a Friday afternoon,
   and a paper Bob Dillon reminded us.
   The authors would thank the anonymous referees for 
   their questions and suggestions.
   
   The computation of the above simulation was conducted on CCS AMD cluster,
    and the mpeg movie was created by MATLAB.